During her time leading the Humanities team, Alison focused on data and device regulation including: appraising the impact of regulatory changes to UK and EU data protection and medical devices regulation for clinical genetics services and medical research; and assessing how in vitro diagnostic devices regulation impacts on IVD device and software development, including the development and implementation of polygenic risk scores.
- Adopting a risk tool for stratification and predictive prevention of oesophageal cancer
- Control of patient information in the COVID-19 era
- Implementing polygenic scores for cardiovascular disease into NHS Health Checks
- Polygenic scores and clinical utility
- Visual identifiers in the care of people with dementia
- Citizen generated data and health: predictive prevention of disease
- The GDPR and genomic data
- Black box medicine and transparencyphgfoundation.org/report/overdiagnosis
- Person centred healthcare
- My healthy future: Overdiagnosis
- Privacy and autonomy
- Algorithms as medical devices
- Regulating algorithms in healthcare: the GDPR and IVDR in practice
- Polygenic scores, risk and cardiovascular disease
- Genomics in mainstream clinical pathways
- Identification and genomic data
- Personalised prevention in breast cancer – the policy landscape
- Variant classification and interpretation – workshop report
- Data sharing to support UK clinical genetics and genomics services
- Pathogen Genomics Into Practice
- Realising Genomics in Clinical Practice
- Stratified Screening for Cancer
- Realising Genomics in Clinical Practice (interim report)
- Next steps in the sequence
- Public health in an era of genome-based and personalised medicine
- Independent response to House of Lords Science and Technology Committee Genomic Medicine report
- Tay Sachs Disease carrier screening in the Ashkenazi Jewish population
- Assessment of the Human Tissue Act
- Somatic genome editing: ethics and regulation
- Somatic genome editing: an overview
- Citizen generated data: the ethics of remote patient monitoring
- What is the IVDR?
- Sharing clinical genomic data for better diagnostics
- The impact of genomic sequencing technologies on patient pathways
- Genomics and the boundary between research and clinical care and treatment
- Moving forward the debate on AI regulation
- Identification and genomic data
- How should UK healthcare prepare for reforms to the EU data protection?
- Review of data security, consent and opt-outs
- Complex diseases need complex solutions – including genomics
- Updated international guidance on human genome and human rights
- Impact of In Vitro Diagnostic Devices regulatory reforms on genetic testing
- Realising Genomics in Clinical Practice – a framework for action
- US clarifies position on secondary findings in clinical genome sequencing
- The impact of genomic sequencing technologies on patient pathways
- AAP guidelines on genetic testing of children: a commentary
- Where are the boundaries for ethical population health policy?
- Do patients have a right to access their clinical sequence data?
- Proposed EU Data Protection reform and public health genomics
- A Principle-Based Approach to Visual Identification Systems for Hospitalized People with Dementia. Brigden, T.V., Mitchell, C., Kuberska, K. Hall, A.. A Principle-Based Approach to Visual Identification Systems for Hospitalized People with Dementia. Bioethical Inquiry (2023). https://doi.org/10.1007/s11673-023-10315-x
- Ethical and legal implications of implementing risk algorithms for early detection and screening for oesophageal cancer, now and in the future. Tanya Brigden, Colin Mitchell, Elizabeth Redrup Hill and Alison Hall. PLOS ONE. 2023 October. https://doi.org/10.1371/journal.pone.0293576
- Ethical and legal considerations influencing human involvement in the implementation of artificial intelligence in a clinical pathway: A multi-stakeholder perspective. Elizabeth Redrup Hill, Colin Mitchell, Tanya Brigden and Alison Hall. Frontiers in Digital Health. 2023 March. https://doi.org/10.3389/fdgth.2023.1139210
- Secondary Use of Personal Health Data: When Is It “Further Processing” Under the GDPR, and What Are the Implications for Data Controllers?
Becker, R., Chokoshvili, D., Comandé, G., Dove, E.S., Hall, A., Mitchell, C., Molnár-Gábor, F., Nicolàs, P., Tervo, S. and Thorogood, A., 2022. European Journal of Health Law, 1(aop), pp.1-29. - Lessons from the pandemic for the future regulation of confidential patient information for research. Colin Mitchell and Alison Hall. Journal of the Royal Society of Medicine. 2023;0(0).
- Applying GDPR roles and responsibilities to scientific data sharing
Regina Becker, Adrian Thorogood, Jasper Bovenberg, Colin Mitchell, Alison Hall, International Data Privacy Law, Volume 12, Issue 3, August 2022, Pages 207–219 - How can we address the uncertainties regarding the potential clinical utility of polygenic score-based tests?
Moorthie S, Hall A, Babb de Villiers C, Janus J, Brigden T, Blackburn L, Kroese M. Future Medicine. 15 March 2022. - Genetic database software as medical devices
Thorogood A, Touré S.B, Ordish J, Hall A, Knoppers B.
Human Mutation. 2018; Vol. 39 Iss.11. pp1702-1712. - A response to the forensic genetics policy initiative’s report “Establishing Best Practice for Forensic DNA Databases”
Samuel, G, Howard H.C, Cornel M, van El C, Hall A, Forzano F, Prainsack B.
Forensic Science International. 2018 5 July; Genetics (online). - Risk stratification, genomic data and the law
Hall A, Finnegan T, Susmita C et al.
J Community Genet. 2018;9:195. - Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure.
Murtagh M, B Mwenza, A Hall et al.
Hum Genomics. 2018;12:24 - Risk stratification, genomic data and the law.
Hall A, Finnegan T, Chowdhury S, Dent T, Kroese M, Burton H.
J Community Genet. 2018; https://doi.org/10.1007/s12687-018-0358-4. [Epub ahead of print] - Genomic medicine and data sharing
Raza S, Hall A.
Br Med Bull. 2017 Sep; 1;123(1):35-45. - Exploring the potential duty of care in clinical genomics under UK law
Mitchell C, Ploem C, Chico V, Ormondroyd E, Hall A, Wallace S, Fay M, Goodwin D, Bell J, Phillips S, Taylor J.C, Hennekam R, Kaye J.
Medical Law International. 2017 Aug 14 [Epub ahead of print] - What ethical and legal principles should guide the genotyping of children as part of a personalised screening programme for common cancer?
Chowdhury S, Hall A, Pashayan N, Pharoah P.
Journal of Medical Ethics. 2013 Mar 1 [Epub ahead of print] PubMed PMID: 23454719 - Ethical issues and best practice in clinically based genomic research: Exeter Stakeholders Meeting Report
Bewshea C, Carrieri D, Hall A, Walker G.
J Med Ethics doi:10.1136/medethics-2016-103530 - Responsible implementation of expanded carrier screening
Henneman L, Borry P, Hall A.
Eur J Hum Genet. 2016 Jun; 24(6)w1-e12. - Known unknowns: building an ethics of uncertainty into genomic medicine
Gaff C, Hall A, Leonard S, Newson A.
BMC Medical Genomics (2016) 9:57 DOI 10.1186/s12920-016-0219-0 - Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening
de Wert G, Dondorp W, Hall A.
European Journal of Human Genetics. 2015 March 18. - Considerations in establishing a post-mortem brain and tissue bank for the study of myalgic encephalomyelitis/chronic fatigue syndrome: a proposed protocol
Bowman E, Goldring K, Gveric D, Hall A, Lacerda E, Nacul L, O’Donovan D, Pheby D.
BMC Research Notes. 2014; (7):370. - Personalized medicine: what’s in a name?
Burton H, Hall A, Kroese M, Pokorska-Bocci A, Sagoo G, Stewart A.
Personalised Medicine. 2014; 11(2):197-210. - Revealing the results of whole-genome sequencing and whole-exome sequencing in research and clinical investigations: some ethical issues
Alberg C, Hall A, Hallowell N, Zimmern R.
Journal of Medical Ethics. Epub 2014 Jul 18. - A Toolkit to assess health needs for congenital disorders in low- and middle-income countries: an instrument for public health action
Nacul L,Stewart A, Alberg C, Chowdhury S, Burton H, Darlison MW, Grollman C, Hall A, Modell B, Moorthie S, Sagoo G, .
Journal of Public Health. 2014 June; 36(2):243-50. doi: 10.1093/pubmed/fdt048 : May 10, 2013 [Epub ahead of print] - Personalised medicine in the UK: challenges of implementation and impact on healthcare system
Burton H, Hall A, Kroese M, Pokorska-Bocci A, Sagoo G.
Genome Medicine. 2014 Apr 25; 6(4):28. - What ethical and legal principles should guide the genotyping of children as part of a personalised screening programme for common cancer?
Burton H, Chowdhury S, Hall A, Pashayan N, Pharoah P.
Journal of Medical Ethics. 2014 Mar; 40(3):163-7. - Public health genomics and personalised prevention: lessons from the COGS project
Burton H, Chowdhury S, Dent T, Hall A, Pashayan N, Pharoah P.
Journal of Internal Medicine. 2013 Nov; 274(5):451-6 - Life insurance: genomic stratification and risk classification
Burton H, Chowdhury S, Dent T, Feze I, Foulkes W, Hall A, Hamet P, Joly Y, Kirwan N, Knoppers B, Macdonald A, Pashayan N, Simard J, Van Hoyweghen I.
European Journal of Human Genetics. 2013 Oct 16. doi: 10.1038/ejhg.2013.228 - Implementing risk-stratified screening for common cancers: a review of potential ethical, legal and social issues
Burton H, Chowdhury S, Dent T, Hall A, Pashayan N, Pharoah P.
Journal of Public Health (Oxf). 2013 Aug 28. - Public health implications from COGS and potential for risk stratification and screening
Burton H, Chowdhury S, Dent T, Hall A, Pashayan N, Pharoah P.
Nature Genetics. 2013 Apr; 45(4):349-51 doi: 10.1038/ng.2582. PubMed PMID: 23535723 - Informatics and clinical genome sequencing: opening the black box
Moorthie S, Hall A, Wright C.
Genet Medicine. 2013 Mar; 15(3):165-71. - Incorporating genomics into breast and prostate cancer screening: assessing the implications
Burton H, Chowdhury S, Dent T, Hall A, Hall P, Lyratzopoulos G, Pashayan N, Pharoah P.
Genetics in Medicine. 2013 Feb 14 doi: 10.1038/gim.2012.167. [Epub ahead of print] PubMed PMID: 23412607. - Stratified cancer screening: the practicalities of implementation.
Burton H, Chowdhury S, Dent T, Eccles D, Eeles R, Hall A, Jbilou J, Lyratzopoulos G, Pashayan N, Pharoah P, Rafi I, Segnan N, T.
Public Health Genomics. 2013;16(3):94-9. - Legal and ethical implications of inherited cardiac disease in clinical practice within the UK
Burton H, Hall A.
Journal of Medical Ethics. 2010; 36: 762-766. - Extending the reach of public health genomics: What should be the agenda for public health in an era of genome-based and “personalized” medicine?
Burke W, Hall A, Karmali M, Khoury M, Knoppers B, Meslin E, Stanley F, Wright C, Zimmern R.
Genetics in Medicine. 2010 Nov; Vol 15. - Regulating direct-to-consumer genetic tests: What is all the fuss about?
Hall A, Wright C, Zimmern R.
Genetics in Medicine. 2010 Oct 1 [Epub ahead of print] - Non-invasive prenatal diagnosis using cell-free fetal DNA technology: applications and implications
Bostanci A, Hall A, Wright C.
Public Health Genomics. 2010; 13(4):246-55. Epub 2010 Apr 15. - Inherited cardiovascular conditions: the challenges of genomic medicine
Alberg C, Burton H, Hall A, Inherited Cardiovascular Conditions Services , Sagoo G, Stewart A.
Heart. 2010 Mar; 96(6):474-6 - Biomarkers, Dementia, and Public Health
Brayne C, Hall A, Matthews F, Wright C.
Annals of the New York Academy of Sciences. 2009; 118:11-19. - Beyond Bristol and Alder Hey: The Future Regulation of Human Tissue
Hall A, Liddell K.
Medical Law Review. 2005; Summer:170-223
