Polygenic scores, risk and cardiovascular disease
Could genomic information help prevent common conditions such as cancer and heart disease?
The potential of polygenic scores to improve risk stratification has reignited enthusiasm around the use of genetic information to help predict and prevent common disease. A new report from the PHG Foundation examines the current reality and future prospects for using polygenic scores for prevention.
Polygenic scores, risk and cardiovascular disease examines the current evidence and readiness for clinical implementation of polygenic scores from the perspective of cardiovascular disease prevention.
This report provides an overview of the current state of cardiovascular disease prevention, and considers the evidence for the implementation of polygenic scores for cardiovascular disease.
If you need to keep abreast with developments in polygenic risk and prevention, read this independent report for:
- Polygenic scores and their applications in health
- An overview of the epidemiology and risk factors of cardiovascular disease
- Risk prediction models and prevention methods in current use for cardiovascular disease
- Ongoing developments in, and the readiness for clinical implementation of polygenic scores for cardiovascular disease
- A detailed assessment of the clinical utility of using polygenic scores as part of an integrated risk tool for cardiovascular disease
The report, Polygenic scores, risk and cardiovascular disease is free to download.
By Sowmiya Moorthie, Chantal Babb de Villiers, Tanya Brigden, Louise Gaynor, Alison Hall, Emma Johnson, Saskia Sanderson, and Mark Kroese