Dr Mark Kroese
Director
Mark joined the Foundation in 2012 as Consultant in Public Health Medicine/Programme Director and was appointed Director in October 2017. He leads the corporate development and strategic management of the Foundation and is responsible for the delivery of its work programme.
Mark graduated in medicine from the University of Edinburgh in 1992 and trained in general practice. Following a post as District Medical Officer in the Caribbean, he returned to the UK to train in public health medicine. Appointed NHS Consultant in Public Health Medicine in 2005, Mark has considerable experience in the NHS. His special interests include healthcare public health, evaluation of genetic tests and the commissioning of clinical genetics services.
He has been a standing member of the Diagnostics Advisory Committee (DAC) of the National Institute for Health and Care Excellence (NICE) (2010-2022) and the Chair of the DAC (2017-2022). Mark has also held the following appointments; public health advisor to the NHS UK Genetic Testing Network (UKGTN) (2006-2018), member of the Council of the Royal College of Physicians of Edinburgh and the Board of the Faculty of Public Health (2017 -2021). He is an accredited clinical supervisor for the HEE East of England Public Health Training Programme.
- Reports
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Implementing polygenic scores for cardiovascular disease into NHS Health Checks
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Personalised prevention in breast cancer – the policy landscape
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Whole exome sequencing in clinical genetics - a health economic evaluation
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Delivering improved access to genetic testing in epithelial ovarian cancer
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Data sharing to support UK clinical genetics and genomics services
- Blogs
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PanelApp – the catalyst to drive improved gene panel testing?
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NIPT for Down’s syndrome – what new evidence means for the UK
- Journal papers
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Melissa Hill; Sian Ellard; Jane Fisher; Naomi Fulop; Marian Knight; Mark Kroese; Jean Ledger; Kerry Leeson-Beevers; Alec McEwan; Dominic McMullan; Laura Blackburn et al. [version 2; peer review: 2 approved]. NIHR Open Res 2022, 2:10
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Moorthie S, Babb de Villiers C, Burton H, Kroese M, Antoniou A.C., Bhattacharjee P, Garcia-Closas M, Hall P, Schmidt M.K.. Preventive Medicine, Vol 159. 6 May 2022.
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Moorthie S, Hall A, Babb de Villiers C, Janus J, Brigden T, Blackburn L, Kroese M. Future Medicine. 15 March 2022.
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Babb de Villiers C, Kroese M, Moorthie S. Journal of Medical Genetics Online First. 6 May 2020.
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Risk stratification, genomic data and the law.
Hall A, Finnegan T, Chowdhury S, Dent T, Kroese M, Burton H.
J Community Genet. 2018; https://doi.org/10.1007/s12687-018-0358-4. [Epub ahead of print]
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Warren-Gash C, Kroese M, Burton H, Pharoah P.
Hered Cancer Clin Pract. 2016 Jun; 1;14:12.
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Realising the promise of non-invasive prenatal testing
Chitty LS, Kroese M.
BMJ. 2015 Apr 10;350:1792.
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Cost Effectiveness of Using Array-CGH for Diagnosing Learning Disability
Sagoo GS, Mohammed S, Barton G, Kroese M et al.
Applied Health Economics and Health Policy. 2015; 13,4, 421-432.
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Personalized medicine: what's in a name?
Burton H, Hall A, Kroese M, Pokorska-Bocci A, Sagoo G, Stewart A.
Personalised Medicine. 2014; 11(2):197-210.
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Borry P, Cornel M, Kroese M, Severin F.
European Journal of Human Genetics. 2014 Sept 24.
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Boustred C, Chitty L, Daley R, Fisher J, Hill M, Howarth A, Kroese M, Lench N, Lewis C, Lo K, Mason S, Mckay F, Morris S, Plagnol V, Spencer K, Wright D.
BMC Pregnancy Childbirth. 2014 Jul 16; 14:229.
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Personalised medicine in the UK: challenges of implementation and impact on healthcare system
Burton H, Hall A, Kroese M, Pokorska-Bocci A, Sagoo G.
Genome Medicine. 2014 Apr 25; 6(4):28.
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A framework for the prioritization of investment in the provision of genetic tests
Alberg C, Burton H, Kroese M, Lakshman R, Whittaker J.
Public Health Genomics. 2010; 13 (7-8) 538-43.
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Evaluation of genetic tests for susceptibility to common complex diseases: why, when and how?
Kroese M, Wright C.
Human Genetics. 2009; doi:10.1007/s00439-009-0767-x
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How can genetic tests be evaluated for clinical use? Experience of the UK Genetic Testing Network.
Kroese M, Zimmern R, Farndon P, Stewart F, Whittaker J.
Eur J Hum Genet. 2007;15:917-21.
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Defining purpose: a key step in genetic test evaluation
Genetics in Medicine. 2007; 9(10):675-681
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HER2 status in breast cancer - an example of pharmacogenetic testing
Kroese M, Pinder S, Zimmern R.
Journal of the Royal Society of Medicine. 2007 Jul; 100(7):326-9
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The evaluation of genetic tests
Journal of Public Health. 2007 May 24; [Epub ahead of print]
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Emery J, Higgins J, Kroese M, Patch C, Sanderson S, Zimmern R.
Genetics in Medicine. 2005; 7(7):495-500
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Genetic tests and their evaluation: Can we answer the key questions?
Genetics in Medicine. 2004; 6(6):475-80
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Health Service Journal. 2003; 113(5868):29