Genomics and risk
Preventing people from becoming ill benefits everyone: individuals, health services and society
To prevent delay and minimise common conditions like heart disease and cancer, we need to know as much as possible about people’s risk of disease. Genomics and other biological information play a critical role, but generating and using health data to understand risk is no simple task. Our work addresses challenges such as the use of polygenic scores, the problem of overdiagnosis and ethical and legal issues.
Report Polygenic scores for cancer
Read our report that provides an overview of what is known about polygenic scores and what they could mean for cancer prediction, prevention and management.
Policy briefing Host genomics for better infectious disease treatment
Host genomics is the field that looks for genetic differences that help to explain the variations in response at certain points of an infection.
Blog Moving forward with breast cancer prevention
27 October 2020
Better understanding of the why, how and who of breast cancer, combined with new technologies, are creating opportunities for personalised prevention
Blog COVID-19 and risk
13 April 2020
Why do some of us at ‘low risk’ get so ill with a viral infection that barely touches others?
Blog After ABC v St George's: a new duty to consider
3 March 2020
New legal duty for healthcare professionals regarding consent is more limited than existing professional guidance
Blog An eye to the future: review of screening programmes in England
30 October 2019
Report's recommendations around accountability and governance of screening programmes could have greatest impact
Blog Using genetic information for disease prevention
22 September 2019
Harnessing knowledge about genetics in the prevention of common diseases such as cardiovascular disease, diabetes and obesity
Report Polygenic scores, risk and cardiovascular disease
18 September 2019
Could genomic information help prevent common conditions such as cancer and heart disease?
Blog Towards personalised prevention?
22 July 2019
UK Government releases Green Paper on public health for consultation, Advancing our health: prevention in the 2020s